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Avenic acid,a new amino acid possessing an iron chelating activity
Authors:Shinji Fushiya  Yoshikazu Sato  Shigeo Nozoe  Kyosuke Nomoto  Tsunematsu Takemoto  Sei-ichi Takagi
Institution:Pharmaceutical Institute, Tohoku University, Aobayama, Sendai Japan 980;Suntory Institute for Bioorganic Research, Shimamotocho, Mishimagun, Osaka Japan 618;Department of Agricultural Chemistry, Iwate University, Ueda, Morioka Japan 020
Abstract:A new amino acid derivative possessing an iron chelating activity was isolated from root washings of water cultured Avena sativa under iron deficient conditions. The structure of this compound, avenic acid A has been determined as 2(S),3′(S),3″(S)-N-3-(3-hydroxy-3-carboxypropylamino)-3-carboxypropyl]-homoserine (1) on the basis of chemical and spectroscopic evidence.
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