A new method for the synthesis of some 9-β-D-arabinofuranosylpurines by a combination of chemical and enzymatic reactions |
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Authors: | Hirokazu Morisawa Takashi Utagawa Takeshi Miyoshi Fumihiro Yoshinaga Akihiro Yamazaki Koji Mitsugi |
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Affiliation: | Central Research Laboratories, Ajinomoto Co., Inc. 1-1 Suzuki-cho, Kawasaki-ku, Kawasaki, 210, Japan. |
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Abstract: | ![]() An enzymatic transarabinosylation between 2-chlorohypoxanthine and 1-β--arabinofuranosyluracil gave 9-β--arabinofuranosyl-2-chlorohypoxanthine which was chemically converted to 9-β--arabinofuranosylguanine and its derivatives. |
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