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Total synthesis of (−) homothienamycin |
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| Authors: | TN Salzmann RW Ratcliffe BG Christensen |
| Institution: | Merck Sharp & Dohme Research Laboratories, Box 2000, Rahway, N. J. 07065 U.S.A. |
| Abstract: | The total synthesis of a ring expanded analog of thienamycin has been developed. The key step utilizes a highly efficient carbene insertion reaction to form the carbacephem ring system. |
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