| a-二芳甲基-b-羰基硫代羧酸酯与肼的环合反应：官能化含5-羟基吡唑基的三芳基甲烷类化合物的合成 |
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| 引用本文： | 丁旭光,于海丰,赵辉,杨勇.a-二芳甲基-b-羰基硫代羧酸酯与肼的环合反应：官能化含5-羟基吡唑基的三芳基甲烷类化合物的合成[J].化学通报,2017,80(12):1152-1155. |
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| 作者姓名： | 丁旭光 于海丰 赵辉 杨勇 |
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| 作者单位： | 鞍山师范学院化学与生命科学学院,鞍山师范学院化学与生命科学学院,鞍山师范学院化学与生命科学学院,鞍山师范学院化学与生命科学学院 |
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| 基金项目： | 辽宁省自然基金项目(201602002),吉林省有机功能分子设计与合成重点实验室开放基金(130028652)和辽宁省教育厅项目(L2015003)资助。 |
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| 摘 要： | 本文研究了合成官能化含5-羟基吡唑基的三芳基甲烷类化合物的a-二芳甲基-b-羰基硫代羧酸酯与肼的环合反应。研究表明,在乙醇介质中,回流条件下, a-二芳甲基-b-羰基硫代羧酸酯与肼能有效进行环合反应,高产率制得5-羟基吡唑基三芳甲烷类化合物。该反应条件温和,产率高,操作简单。
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| 关 键 词： | 硫代羧酸酯 三芳基甲烷 环合反应 5-羟基吡唑 |
| 收稿时间： | 2017/5/30 0:00:00 |
| 修稿时间： | 2017/8/20 0:00:00 |
Cyclization of a-Diaryl methyl-b-oxothioesters and hydrazine: Synthesis of Functionalized 5-Hydroxy Pyrazolyl-ContainingTriarylmethanes |
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| Ding Xuguang,Yu Haifeng,Zhao Hui and Yang Yong.Cyclization of a-Diaryl methyl-b-oxothioesters and hydrazine: Synthesis of Functionalized 5-Hydroxy Pyrazolyl-ContainingTriarylmethanes[J].Chemistry,2017,80(12):1152-1155. |
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| Authors: | Ding Xuguang Yu Haifeng Zhao Hui and Yang Yong |
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| Institution: | School of Chemistry and Life Science,Anshan Normal University,School of Chemistry and Life Science,Anshan Normal University,School of Chemistry and Life Science,Anshan Normal University,School of Chemistry and Life Science,Anshan Normal University |
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| Abstract: | We developed the cyclization reactions of ?-diaryl methyl-?-ketothioesters and hydrazine for the synthesis of functionalized 5-hydroxy pyrazolyl-containing triarylmethanes. Our studies had shown that the cyclization reactions of ?-diaryl methyl-?-ketothioesters and hydrazine smoothly performed in refluxing EtOH, affording functionalized 5-hydroxy pyrazolyl-containing triarylmethanes in excellent yield. Mild reaction conditions,easy work-up procedure, and excellent yields are some notable advantages of our work. |
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| Keywords: | thioester triarylmethane cyclization reaction 5-hydroxy pyrazole |
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