|
|||||
|
|
Toward breast cancer resistance protein (BCRP) inhibitors: design, synthesis of a series of new simplified fumitremorgin C analogues |
|
| Authors: | Guofeng Wu Lanrong Bi Chao Wang Jingfang Ju Shiqi Peng |
| Institution: | a College of Pharmaceutical Sciences, Peking University, Beijing 100083, PR China b College of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, PR China c Mitchell Cancer Institute, University of South Alabama, 307 N. University Blvd, Mobile, AL 36688-0002, USA d UMR 6226 CNRS, Groupe ‘Ciblage et Autoassemblages Fonctionnels’, Université de Rennes I, 263 Av. du Général Leclerc, F-35042 Rennes Cedex, France |
| Abstract: | In this study, we report the design and synthesis of a series of new simplified fumitremorgin C analogues. The preliminary biological study indicated some of these simplified fumitremorgin C might be developed into breast cancer resistance inhibitors. |
| Keywords: | Fumitremorgin C analogues Breast cancer resistance protein inhibitors Enantioselective synthesis Racemization Coupling |
| 本文献已被 ScienceDirect 等数据库收录！ | |