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Highly efficient Pd‐PEPPSI‐IPr catalyst for N‐(4‐pyridazinyl)‐bridged bicyclic sulfonamides via Suzuki–Miyaura coupling reaction |
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| Authors: | Mallikarjuna Reddy Sura N Reddy Bijivemula Sreekanth Reddy Pogula Venkata Krishna Reddy Motakatla Pathak Madhvesh Vasu Govardhana Reddy Peddiahgari |
| Institution: | 1. Department of Chemistry, Vellore Institute of Technology, Vellore, Tamil Nadu, India;2. Department of Chemistry, Yogi Vemana University, Kadapa, Andhra Pradesh, India |
| Abstract: | A protocol for the Suzuki–Miyaura coupling of novel 2‐(6‐chloropyridazin‐3‐yl)‐5‐(aryl/heteroarylsulfonyl)‐2,5‐diazabicyclo2.2.1]heptanes and heteroarylboronic acids to afford variety of coupled products was realized. Pd‐PEPPSI‐IPr catalyst was found to be a powerful and reusable catalyst under relatively mild reaction conditions. |
| Keywords: | 3‐pyridazinyl‐2 5‐diazabicycloheptane sulfonamides heteroarylboronic acids Pd‐PEPPSI‐IPr Suzuki– Miyaura coupling reaction |