Highly efficient AgNO3‐catalyzed approach to 2‐(benzo[d]azol‐2‐yl)phenols from salicylaldehydes with 2‐aminothiophenol, 2‐aminophenol and benzene‐1,2‐diamine |
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| Authors: | Xinwei He Yuhao Wu Wenjing Jin Xiaoshun Wang Cong Wu Yongjia Shang |
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| Affiliation: | Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule‐Based Materials (State Key Laboratory Cultivation Base), College of Chemistry and Materials Science, Anhui Normal University, Wuhu, People's Republic of China |
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| Abstract: | A new, convenient and efficient AgNO3‐catalyzed strategy for the preparation of 2‐(benzo[d]azol‐2‐yl)phenol derivatives in good to excellent yields (63–98%) is described. The reaction proceeds via condensation/intramolecular nucleophilic addition/oxidation process between substituted salicylaldehydes and 2‐aminothiophenol, 2‐aminophenol or benzene‐1,2‐diamine under mild reaction conditions. Notably, this reaction utilizes cheap AgNO3 as a readily available and low‐cost benign oxidant at low catalyst loadings with excellent functional group tolerance. |
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| Keywords: | condensation oxidation phenols salicylaldehydes silver nitrate |
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