Enzyme-free signal amplification in the DNAzyme sensor via target-catalyzed hairpin assembly |
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| Authors: | Zheng Ai-Xian Li Juan Wang Jin-Ru Song Xiao-Rong Chen Guo-Nan Yang Huang-Hao |
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| Institution: | The Key Lab of Analysis and Detection Technology for Food Safety of the MOE, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, P. R. China. |
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| Abstract: | A simple, highly sensitive and enzyme-free DNAzyme sensor based on target-catalyzed hairpin assembly is developed, which permits detection of 0.1 pM target DNA. Furthermore, this DNAzyme sensor is capable of detecting target DNA in real samples because of its high selectivity. |
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