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Sonication induced sheet formation at the air-water interface
Authors:Satheeshkumar K S  Jayakumar R
Affiliation:Bio Organic Laboratory, Central Leather Research Institute, Adyar, Chennai 600 020, India.
Abstract:
A hydrophobic pentadecapeptide, AGAAAA-GAVVGGLGG (1), part of the prion sequence PrP (106-127), on fresh aqueous dissolution takes a mixture of random and sheet conformations which forms a stable monolayer with a high beta-sheet content when compressed at the air-water interface. This also develops into a kinetically stabilized beta-sheet structure on sonication.
Keywords:
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