From carboxylic acids to the trifluoromethyl group using BrF3 |
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| Authors: | Or Cohen Shlomo Rozen |
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| Institution: | a School of Chemistry, Tel-Aviv University, Tel-Aviv 69978, Israel
b Radiochemistry, Hadassah Hospital, Hebrew University, 91120 Jerusalem, Israel |
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| Abstract: | Organic trifluoromethyl derivatives were made from aromatic and aliphatic carboxylic acids by transforming them first into the corresponding dithioesters followed by reaction with bromine trifluoride under mild conditions (0 °C, 2 min). |
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