Synthesis of pyrroloazepinones: platinum- and gold-catalyzed cyclization reactions of alkynes |
| |
| Authors: | Marina Gruit |
| |
| Affiliation: | Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock, Germany |
| |
| Abstract: | The synthesis of potentially bioactive pyrroloazepinones based on the catalytic intramolecular cyclization of alkyne-substituted 1H-pyrrole-2-carboxylic acid amides has been developed. In the presence of either H2PtCl6·6H2O at 120 °C or AuCl3 at room temperature pyrrolo[3,2-c]azepin-4-ones are formed. |
| |
| Keywords: | Cyclization Platinum Gold Pyrroles Alkynes |
| 本文献已被 ScienceDirect 等数据库收录！ |
