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Sodium stearate-catalyzed multicomponent reactions for efficient synthesis of spirooxindoles in aqueous micellar media
Authors:Li-Min Wang  Ning Jiao  Jun Qiu  Jian-Jun Yu  Jin-Qian Liu  Feng-Lou Guo  Ying Liu
Affiliation:Key Laboratory for Advanced Materials & Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, People's Republic of China
Abstract:
A new type of Lewis base-surfactant-combined catalyst (LBSC), sodium stearate, was applied as a catalyst in three-component one-pot reaction involving isatin, malononitrile, and 1,3-dicarbonyl compounds to afford the corresponding spirooxindoles derivatives in good yields (91-97%) under aqueous micellar media.
Keywords:Sodium stearate   Spirooxindole   Aqueous micellar media   Multicomponent reactions
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