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Cytotoxic terpenoids from Dasyscyphus niveus
Authors:Veronica Rojas de la Parra  Timm Anke
Affiliation:a Department of Organic Chemistry, University of Lund, PO Box 124, S-22100 Lund, Sweden
b TU Kaiserslautern, Department of Biotechnology, D-67663 Kaiserslautern, Germany
Abstract:
Three novel tetracyclic terpenoids, of which two possess potent cytotoxic activities towards various mammalian cell lines, were isolated from extracts of the fermentation broth of the ascomycete Dasayscyphus niveus. The structures of the compounds, named dasyscyphins A-C, were determined with spectroscopic techniques.
Keywords:Dasayscyphus niveus   Terpenoids   Dasyscyphin   Cytotoxicity   Structure determination
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