Synthesis of functionalized analogs of pyochelin, a siderophore of Pseudomonas aeruginosa and Burkholderia cepacia |
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| Authors: | Freddy Rivault Elias Sakr |
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| Institution: | Métaux et Microorganismes: Chimie, Biologie et Applications, Département des Récepteurs et Protéines Membranaires, UMR7175 Institut Gilbert Laustriat, École Supérieure de Biotechnologie de Strasbourg, Boulevard Sébastien Brant F-67400 Illkirch, France |
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| Abstract: | Using an improved synthesis of pyochelin, a siderophore common to several pathogenic Pseudomonas species, three functionalized pyochelin analogs were efficiently synthesized starting from appropriate 2-hydroxybenzonitriles. |
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| Keywords: | Pseudomonas Burkholderia Cystic fibrosis Siderophore Pyochelin Antibiotic Trojan horse conjugate Iran uptake |
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