Tris-hydroxymethylaminomethane (THAM): An efficient organocatalyst in diversity-oriented and environmentally benign synthesis of spirochromenes |
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| Authors: | Supriya S Khot Prashant V Anbhule Uday V Desai Prakash P Wadgaonkar |
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| Institution: | 1. Department of Chemistry, Shivaji University, Kolhapur 416004, India;2. Polymer Science and Engineering Division, CSIR, National Chemical Laboratory, Pune 411008, India |
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| Abstract: | Tris-hydroxymethylaminomethane has been demonstrated to be an efficient organocatalyst in diversity-oriented synthesis of medicinally prevalent spirochromenes by one-pot, three-component reactions between isatins, malononitrile, and enolizable C | |
| Keywords: | Multicomponent synthesis Tris-hydroxymethylaminomethane Organocatalysis Spirochromenes Green chemistry |
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