Lab‐on‐a‐Chip Reactor Imaging with Unprecedented Chemical Resolution by Hadamard‐Encoded Remote Detection NMR |
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| Authors: | Dr Ville‐Veikko Telkki Dr Vladimir V Zhivonitko M Sc Anne Selent Dr Gianmario Scotti M Sc Jarmo Leppäniemi Prof Sami Franssila Prof Igor V Koptyug |
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| Institution: | 1. NMR Research Group, Department of Physics, University of Oulu, P.O. Box 3000, 90014 Oulu (Finland) http://cc.oulu.fi/～nmrwww/;2. Laboratory of Magnetic Resonance Microimaging, International Tomography Center SB RAS, 3A Institutskaya St., Novosibirsk 630090 (Russia);3. Novosibirsk State University, Pirogova St. 2, Novosibirsk 630090 (Russia);4. Department of Materials Science and Engineering, Aalto University, P.O. Box 16200, 00076 Aalto (Finland) |
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| Abstract: | The development of microfluidic processes requires information‐rich detection methods. Here we introduce the concept of remote detection exchange NMR spectroscopy (RD‐EXSY), and show that, along with indirect spatial information extracted from time‐of‐flight data, it provides unique information about the active regions, reaction pathways, and intermediate products in a lab‐on‐a‐chip reactor. Furthermore, we demonstrate that direct spatial resolution can be added to RD‐EXSY efficiently by applying the principles of Hadamard spectroscopy. |
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| Keywords: | Hadamard spectroscopy lab‐on‐a‐chip microfluidics NMR spectroscopy reactor imaging |
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