Laboratoire de Chimie Physique, Minérale et Bioinorganique, Faculté de Pharmacie, EA401, rue J.B. Clément, Châtenay-Malabry 92290, France
Abstract:
Progesterone is known to exist under different crystallographic forms in the solid state. The thermodynamic stable form (I), melts at 129.2 °C (402.35 K) under atmospheric pressure. After melting and cooling a metastable form (II) can be obtained which melts at 122 °C (395.15 K). This uncommon behaviour can be explained with the theory of nucleation, only if heat capacity of the different forms are known.