Shortcut to fmoc-protected phosphinic pseudodipeptidic blocks |
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| Authors: | Matziari Magdalini Yiotakis Athanasios |
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| Affiliation: | Laboratory of Organic Chemistry, Department of Chemistry, University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece. |
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| Abstract: | A three-component condensation reaction of Fmoc-carbamate, aldehydes, and alkylphosphinic acids provides a new, direct, and efficient method for synthesizing Fmoc-protected phosphinic pseudodipeptidic blocks, directly usable for solid-phase peptide synthesis. [reaction: see text] |
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