Enantiomers of sterically hindered n-aryl-4-pyridones: Chromatographic enrichment and thermal interconversion |
| |
| Authors: | M Mintas Z Orhanovi? K Jakop?i? H Koller G Stühler A Mannschreck |
| |
| Institution: | Department of Organic Chemistry, Faculty of Technology, University of Zagreb, Maruli?ev trg 20, Y-41000 ZagrebYugoslavia;Institut für Organische Chemie, Universität Regensburg, Universitätsstrasse 31, D-8400 RegensburgFrg |
| |
| Abstract: | N-Aryl-4-pyridones 1–6 were synthesized by condensation of the corresponding 4-pyrone with anilines. The enrichment of the enantiomers was achieved by liquid chromatography on triacctylcellulose, enantiomeric purities of(+)-1 and (+ )-2 being measured by 1H-NMR in the presence of an optically active auxiliary. Barriers to partial rotation about the C-N bond in 1-4 were determined and compared with corresponding biphenyls. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
