| 盐酸环丙沙星的合成 |
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| 引用本文： | 李和平,江天成.盐酸环丙沙星的合成[J].化学研究与应用,1996,8(2):292-294. |
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| 作者姓名： | 李和平 江天成 |
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| 作者单位： | 郑州粮食学院精细化工系，天津河北制药厂 |
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| 摘 要： | 以３－氯－４－氟苯胺为起始原料，经六步反应合成盐酸环丙沙星，总收率达４２．３％，高于现有文献报道值。经元素分析，红外光谱和核磁共振谱确认了产物的结构。
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| 关 键 词： | 盐酸环丙沙星 合成 氟苯胺 |
SYNTHESIS OF CIPROFLOXACIN HYDROCHLORIDE MONOHYDRATE |
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| Li Heping.SYNTHESIS OF CIPROFLOXACIN HYDROCHLORIDE MONOHYDRATE[J].Chemical Research and Application,1996,8(2):292-294. |
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| Authors: | Li Heping |
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| Abstract: | Ciprofloxacin hydrochloride monohydrate was synthesized from 3-chloro-4-fluoaniline by six-step process.The overall yield could be up to 42. 4%.The structure of products was identified by elementary analysis, infrared spectroscopy and nuclear magnetic spectrum. |
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| Keywords: | Ciprofloxacin hydrochloride monohydrate Synthesis 3-Chloro-4-fluoraniline |
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