A facile method for fluoroalkylation of aniline and its derivatives |
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| Affiliation: | 1. Politecnico di Milano, Milano, Italy;2. Consorzio INSTM, Firenze, Italy |
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| Abstract: | ![]()
In the presence of tetrakis(triphenylphosphine)nickel, fluoroalkylation reactions of aniline and its derivatives occur under mild conditions, giving good yields of the corresponding o- and p-fluoroalkylaniline. The reaction shows regioselectivity. The hydrolytic behaviors of the products are also described. |
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