N-Methyl-D-aspartic Acid (NMDA) in the nervous system of the amphioxus Branchiostoma lanceolatum |
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| Authors: | Salvatore D'Aniello George H Fisher Enza Topo Gabriele Ferrandino Jordi Garcia-Fernàndez Antimo D'Aniello |
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| Affiliation: | 1.Departament de Genètica, Facultat de Biologia,Universitat de Barcelona,Barcelona,Spain;2.Department of Chemistry,Barry University,Miami Shores,USA;3.Laboratory of Neurobiology,Stazione Zoologica "A. Dohrn",Napoli,Italy |
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| Abstract: | Background NMDA (N-methyl-D-aspartic acid) is a widely known agonist for a class of glutamate receptors, the NMDA type. Synthetic NMDA elicits very strong activity for the induction of hypothalamic factors and hypophyseal hormones in mammals. Moreover, endogenous NMDA has been found in rat, where it has a role in the induction of GnRH (Gonadotropin Releasing Hormone) in the hypothalamus, and of LH (Luteinizing Hormone) and PRL (Prolactin) in the pituitary gland. |
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