Synthesis and Antitubercular and Antibacterial Activities of Triethylammonium 2-Acetamido-3,4,6-tri-<Emphasis Type="Italic">O</Emphasis>-acetyl-2-deoxy-D-glucopyranosyl Decyl Phosphate |
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Authors: | B F Garifullin R R Sharipova A D Voloshina M A Kravchenko V E Kataev |
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Institution: | 1.Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center,Russian Academy of Sciences,Kazan,Russia;2.Ural Research Institute of Phthisiopulmonology,Yekaterinburg,Russia |
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Abstract: | Phosphorylation of 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucose at the anomeric hydroxy group gave previously unknown triethylammonium 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucopyranosyl phosphonate, and successive treatment of the latter with decan-1-ol and aqueous iodine afforded triethylammonium 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranosyl phosphate. |
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