| 含2-三氟甲基苯并咪唑的双噁二唑硫醚及其亚砜衍生物的合成 |
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| 引用本文： | 刘晨江,时天昊,李燕萍.含2-三氟甲基苯并咪唑的双噁二唑硫醚及其亚砜衍生物的合成[J].有机化学,2007,27(8):985-988. |
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| 作者姓名： | 刘晨江 时天昊 李燕萍 |
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| 作者单位： | 新疆大学化学化工学院,石油天然气精细化工教育部重点实验室,乌鲁木齐,830046 |
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| 基金项目： | 国家自然科学基金（No.20662009）资助项目. |
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| 摘 要： | 芳甲酰肼和氯乙酸在二甲苯中反应生成了一系列的2-芳基-5-氯甲基-1,3,4-噁二唑(1a～1j), 继而与2-(2-三氟甲基苯并咪唑-1-亚甲基)-5-巯基-1,3,4-噁二唑(2)在乙醇-水的溶液中反应得到了一系列的含2-三氟甲基苯并咪唑的双噁二唑硫醚3a～3j, 再用硝酸氧化得到相应的亚砜衍生物4a～4j. 化合物的结构经元素分析, IR, 1H NMR确证.
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| 关 键 词： | 2-三氟甲基苯并咪唑 1 3 4-噁二唑 硫醚 亚砜 合成 |
| 收稿时间： | 2006-7-21 |
| 修稿时间： | 2006-07-212006-10-17 |
Synthesis of Bisoxadiazolyl Substituted Sulfides and Sulfoxides Containing 2-Trifluoromethylbenzimidazol-1-yl Group |
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| LIU,Chen-Jiang,SHI,Tian-Hao,LI,Yan-Ping.Synthesis of Bisoxadiazolyl Substituted Sulfides and Sulfoxides Containing 2-Trifluoromethylbenzimidazol-1-yl Group[J].Chinese Journal of Organic Chemistry,2007,27(8):985-988. |
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| Authors: | LIU Chen-Jiang SHI Tian-Hao LI Yan-Ping |
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| Institution: | Key Laboratory of Petroleum and Gas Fine Chemicals of Ministry of Education, College of Chemistry and Chemical Engineering, Xinjiang University, Ulumqi 830046 |
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| Abstract: | A series of novel bisoxadiazolyl sulfides containing 2-trifluoromethylbenzimidazol-1-yl group 3a～3j and the corresponding sulfoxide derivatives 4a～4j were synthesized via condensation of 2-aryl-5-chloromethyl-1,3,4-oxadiazoles (1a～1j) with 2-(2-trifluoromethylbenzimidazol-1-ylmethyl)-5- mercapto-1,3,4-oxadiazoles (2) followed by oxi-dation with HNO3. The structures of these compounds were confirmed by elemental analysis, IR and 1H NMR spectra. |
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| Keywords: | 2-trifluoromethylbenzimidazole 1 3 4-oxadiazole sulfide sulfoxide synthesis |
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