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Ruthenium(II)‐Catalyzed Synthesis of Spirobenzofuranones by a Decarbonylative Annulation Reaction |
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| Authors: | Partha P Kaishap Gauri Duarah Dr Bipul Sarma Prof?Dr Dipak Chetia Dr Sanjib Gogoi |
| Institution: | 1. Chemical Sciences & Technology Division, CSIR-North East Institute of Science and Technology, Jorhat-, India;2. Department of Chemical Sciences, Tezpur University, Napaam, Tezpur-, India;3. Department of Pharm. Sciences, Dibrugarh University, Dibrugarh, India |
| Abstract: | The first decarbonylative insertion of an alkyne through C?H/C?C activation of six‐membered compounds is reported. The Ru‐catalyzed reaction of 3‐hydroxy‐2‐phenyl‐chromones with alkynes works most efficiently in the presence of the ligand PPh3 to provide spiro‐indenebenzofuranones. Unlike previously reported metal‐catalyzed decarbonylative annulation reactions, in the present decarbonylative annulation reaction, the annulation occurs before extrusion of carbon monoxide. |
| Keywords: | annulation benzofuranones C− H activation decarbonylation ruthenium catalysis |