Bacteria-based AND logic gate: a decision-making and self-powered biosensor |
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| Authors: | Li Zhongjian Rosenbaum Miriam A Venkataraman Arvind Tam Tsz Kin Katz Evgeny Angenent Largus T |
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| Institution: | Department of Biological and Environmental Engineering, Cornell University, 214 Riley-Robb Hall, Ithaca, NY 14853, USA. |
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| Abstract: | We developed a bacteria-based AND logic gate using a Pseudomonas aeruginosa lasI/rhlI double mutant with two quorum-sensing signaling molecules as the input signals. We showed a distinct electrical output signal, despite the complexity and continuous regulation of metabolic reactions of living cells. |
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