| 稀土氮杂环配合物的合成、 结构及抑菌活性 |
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| 引用本文： | 李冰,王学敏,白凤英,刘淑清.稀土氮杂环配合物的合成、 结构及抑菌活性[J].高等学校化学学报,2019,40(4):632. |
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| 作者姓名： | 李冰 王学敏 白凤英 刘淑清 |
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| 作者单位： | 辽宁师范大学化学化工学院,大连,116029;大连医科大学基础医学院生物化学教研室,大连,116044 |
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| 基金项目： | 国家自然科学基金(批准号: 21571091)和辽宁省科学事业公益研究基金(批准号: 20170055)资助. |
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| 摘 要： | 采用溶液合成法, 在室温下合成了一系列稀土配合Ln(IAA)2(phen)2]·(NO3)Ln=Ce(1), Gd(2), Tb(3), Dy(4), Ho(5), HIAA=吲哚乙酸, phen=1,10-菲咯啉], 并通过元素分析、 红外光谱、 热重分析、 X射线单晶衍射、 X射线粉末衍射等方法对配合物进行了表征. 结果表明, 配合物15具有相同的结构, 对配合物2的单晶结构分析表明, 配合物2为超分子网络结构, 通过分子间氢键形成2D网络, 中心金属Gd(Ⅲ)为九配位, 具有单帽四方反棱柱几何构型. 此外, 对该系列配合物进行了抑菌活性的研究, 得到了抑菌活性与配合物组成的构效关系.
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| 关 键 词： | 稀土配合物 吲哚乙酸 1 10-菲咯啉 晶体结构 抑菌活性 |
| 收稿时间： | 2018-10-29 |
Synthesises,Structures and Antibacterial Activities of a Series of Rare Earth Nitrogen Heterocyclic Complexes† |
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| LI Bing,WANG Xuemin,BAI Fengying,LIU Shuqing.Synthesises,Structures and Antibacterial Activities of a Series of Rare Earth Nitrogen Heterocyclic Complexes†[J].Chemical Research In Chinese Universities,2019,40(4):632. |
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| Authors: | LI Bing WANG Xuemin BAI Fengying LIU Shuqing |
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| Institution: | 1. College of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian 116029, China2. Department of Biochemistry, School of Basic Medical Sciences, Dalian Medical University, Dalian 116044, China |
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| Abstract: | A series of rare earth metal complexes, Ln(IAA)2(phen)2]·(NO3)Ln=Ce(1), Gd(2), Tb(3), Dy(4), Ho(5). HIAA=indole acetic acid, phen=1,10-phenanthroline], was synthesized via the solution synthesis method at room temperature. The structures of the complexes were characterized by elemental analysis, infrared spectroscopy, thermogravimetric analysis, X-ray single crystal diffraction and powder polycrystalline diffraction. Structural analyses show that complex 2 has a supramolecular network structure and its 2D network structure is formed through intermolecular hydrogen bonds. The central metal Gd(Ⅲ) is nine-coordinated with a single-capped quadrilateral inverse prism geometry. In addition, the antibacterial activity of the five complexes was studied, and the structure-activity relationship between antibacterial activity and composition of complexes was analysized. |
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| Keywords: | Rare earth complex Indole acetic acid 1 10-Phenanthroline Crystal structure Antibacterial activity |
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