Application of negative chemical ionization mass spectrometry to the structure elucidation of perfluorochemicals and related compounds |
| |
Authors: | Kirby V Scherer Kouichi Yamanouchi Taizo Ono |
| |
Institution: | Department of Chemistry, University of Southern California, Los Angeles, CA 90007 U.S.A. |
| |
Abstract: | The negative chemical ionization mass spectra of representative perfluorinated alkanes, cycloalkanes, ethers and tertiary amines have been examined, using Ar at about 0.5 torr as the reagent gas. The compounds chosen are typical of those under study as components of fluorochemical emulsion blood substitutes. Many such PFC's, particularly those with cyclic or branched structures, give intense molecular ions; most give simple spectra with a few major fragment ions at high mass, in marked contrast to the EI spectra which are dominated by m/e 69 (CF3+) and 131 (C3F5+) of no value for structure elucidation. NCI-GC/MS is more sensitive than conventional EI-GC/MS and promises to be more generally useful for structure determination. Specific examples from the various classes will be presented, and their NCI and EI mass spectra compared. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|