Synthesis and Crystal Structure of N—tert—butyl—N′—（2，4—dichlorobenzoyl）—N—[1—（4—chlorophenyl）—1,4—dihydro—6—methylpyridazine—4—oxo—3—carbonyl]hydrazine

1 INTRODUCTIONPyridazinone derivatives represent one of the most active classes of compounds possessing a wide spectra of biological activity. They are widely used in pharmaceuticals and agrochemicals1,2]. Rohm- Haas Company had reported that N-tert-butyl- dibenzoylhydrazine exhibits excellent insecti- cides3, 4] and t-butyl plays an important role in the insecticide activity 5]. In the previous paper, we had reported that 1-aryl-1,4-dihydro-3- acylhydrazino- carbonyl-4-one-6-methylpy…

Synthesis and Crystal Structure of N-tert-butyl-N′-(2,4-dichlorobenzoyl)-N-[1-(4-chlorophenyl)-1, 4-dihydro-6-methylpyridazine-4-oxo-3- carbonyl] hydrazine

The title compound N-tert-butyl-N(-(2,4-dichlorobenzoyl)-N-1-(4-chlorophenyl)- 1,4-dihydro-6-methylpyridazine-4-oxo-3-carbonyl]hydrazine (C23H_21N4O3Cl3)2·1.5H_2O, Mr = 1042.60] was prepared by the reaction of 1-(4-chlorophenyl)-1,4-dihydro-4-oxo-6- methylpyridazine-3-carboxylic acid with chloroformate ethyl ester, then with N′-tert-butyl-N- (2,4-dichlorobenzoyl) hydrazine in the present of triethylamine. The crystal structure has been determined by X-ray diffraction. The crystal belongs to Monoclinic, space group P21/c, with unit cell constants a =11.4948(9), b=12.7495(10), c=35.854(3) ?, β =92.964(2)°, Z=4, V=5247.6(7) ?3, Dc = 1.320 Mg/m3, F(000) = 2156 , μ (MoKa)= 0.385, R = 0.0661, wR = 0.1875, for 9151 observed reflections( I >2σ(I)). The structure is a dimer linked by intermolecular hydrogen bond which can be observed between N(1)- H...O(6), N(5)- H...O(3). The distances are 2.068 and 2.027? respectively.