|
|||||
|
|
Synthesis of the Ethyl Esters of 4-(3-Pyridyl)- and 4-(4-Pyridyl)-2-oxobutenoic Acids |
|
| Authors: | Dz Sile V A Slavinska G Rozental J Popelis Yu Balodis E Lukevics |
| Institution: | (1) Latvian Institute of Organic Synthesis, Riga, LV-1006, Latvia |
| Abstract: | We have developed a method for the synthesis of ethyl 4-(3-pyridyl)- and 4-(4-pyridyl)-2-oxobutenoates by condensation of 3-pyridinecarbaldehyde and 4-pyridinecarbaldehyde monohydrate respectively with ethyl pyruvate, esterifiction of the target acids, and hydrolysis of the corresponding ethyl ester ketals in the presence of FeCl3·6H2O. |
| Keywords: | ketals 3- and 4-pyridinecarbaldehydes 2-oxobutenoate esters ketal hydrolysis aldehyde condensations |
| 本文献已被 SpringerLink 等数据库收录！ | |