A novel acid-catalyzed C5-alkylation of oxindoles using alcohols |
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Authors: | Reddy Chada Raji Jithender Enukonda Krishna Gaddam Reddy Gunreddy Venkat Jagadeesh Bharatam |
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Affiliation: | Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad, India. rajireddy@iict.res.in |
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Abstract: | A novel C5-alkylation of oxindoles using alcohols as alkylating agents under acid catalysis is described for the first time. The reactions of various benzylic, allylic and propargylic alcohols are studied to obtain the corresponding 5-substituted oxindoles in good yields. |
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