Synthesis of peptides based onβ-(N1-uracilyl)-α-alanine |
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Authors: | M. Yu. Lidak R. A. Paégle V. É. Straume D. É. Shnore Yu. P. Shvachkin |
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Affiliation: | (1) Institute of Organic Synthesis, Academy of Sciences of the Latvian SSR the Latvia, Riga;(2) M. V. Lomonosov Moscow State University, USSR |
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Abstract: | The synthesis of peptides which include a DL--(N1-uracilyl)--alanine (DL-willardiine) residue as an N-terminal or C-terminal group was investigated, dipeptides of DL-willardiine with glycine and L-tyrosine were obtained, and DL-willardiyl-DL-willardiine was synthesized; the latter is the simplest representative of the family of monotonic homopeptides which contain, as a repeating side substituent, a natural nucleic base capable of participation in intermolecular interactions of the complementary type.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 404–408, March, 1971. |
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