Sodium methoxide: a simple but highly efficient catalyst for the direct amidation of esters |
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| Authors: | Ohshima Takashi Hayashi Yukiko Agura Kazushi Fujii Yuka Yoshiyama Asako Mashima Kazushi |
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| Affiliation: | Graduate School of Pharmaceutical Sciences, Kyushu University and CREST, JST, Fukuoka, Japan. ohshima@phar.kyushu-u.ac.jp |
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| Abstract: | ![]()
A simple NaOMe catalyst provides superior accessibility to a wide variety of functionalized amides including peptides through direct amination of esters in an atom-economical and environmentally benign way. |
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