Amino Acid Derivatives, VII [1]: Synthesis and Antiviral Evaluation of α-Amino Acid Esters Bearing an Indazole Side Chain |
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Authors: | Adel A-H Abdel-Rahman |
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Institution: | (1) Department of Chemistry, Faculty of Science, Menoufia University, Shebin El-Koam, Egypt;(2) Department of Botany, Faculty of Science, Menoufia University, Shebin El-Koam, Egypt |
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Abstract: | A series of peptide and dipeptide derivatives conjugated with an indazole residue were synthesized. The new compounds were
evaluated in vitro for cytotoxicity against Hepatitis-A virus (HAV-27), Herpes Simplex virus-1 (HSV-1), and Hepatitis-B virus (HBV) and showed moderate to high activity. |
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