Cyclization under mild conditions of cysteine containing peptides |
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| Authors: | G. Zanotti F. Pinnen G. Lucente |
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| Affiliation: | 1. Centro di Studio per la Chimica del Farmaco del CNR, Università di Roma, 00185, Roma, Italy.;2. Istituto di Chimica Farmaceutica, Università di Roma, P.le Aldo Moro, 00185, Roma, Italy |
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| Abstract: | Cyclization of di- and tripeptides containing cysteine as N-terminal residue is reported. The preferred cyclization patterns and the nature of the products (diketopiperazine, aza-cyclol, peptide thiolactone) are discussed. |
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