Department of Chemistry, University of Gothenburg, 41296 Gothenburg (Sweden), Fax: (+46)?31‐772‐3840
Abstract:
Voilà, optical activity : Both enantiomers of 1‐chloroindene have been synthesized in high selectivity from solely achiral starting materials, and without using optically active catalysts (see scheme). These symmetry‐breaking syntheses provide a proof‐of‐concept for a new approach to asymmetric synthesis. NCS=N‐chlorosuccinimide.
