The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, 91904 (Israel), Fax: (+972)?2‐652‐7715
Abstract:
Open sesame : Aptamer–substrate complexes activate the coherent operation of two tweezers that act as a “SET–RESET” logic system. Each tweezer cycles between a fluorescent open state and a closed quenched state (Q=quencher, F=fluorophore) when triggered by adenosine monophosphate (AMP) and adenosine deaminase (AD).