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Coherent Activation of DNA Tweezers: A “SET–RESET” Logic System
Authors:Johann Elbaz  Michal Moshe  Itamar Willner Prof
Institution:The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, 91904 (Israel), Fax: (+972)?2‐652‐7715
Abstract:Open sesame : Aptamer–substrate complexes activate the coherent operation of two tweezers that act as a “SET–RESET” logic system. Each tweezer cycles between a fluorescent open state and a closed quenched state (Q=quencher, F=fluorophore) when triggered by adenosine monophosphate (AMP) and adenosine deaminase (AD).
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Keywords:aptamers  DNA machines  logic gates  molecular devices  tweezers
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