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An Optical Approach for Drug Screening Based on Light‐Harvesting Conjugated Polyelectrolytes |
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| Authors: | Lingling An Libing Liu Dr Shu Wang Prof Guillermo C Bazan Prof |
| Institution: | 1. Beijing National Laboratory for Molecular Sciences, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190 (P.R. China), Fax: (+86)?10‐6263‐6680;2. Departments of Chemistry and Materials, Center for Polymers and Organic Solids, University of California, Santa Barbara, CA 93106‐9510 (USA) |
| Abstract: | Drugs turn the light off : Conjugated polyelectrolytes (CPEs) have been used in fluorescent assays for real‐time screening of small molecules that prevent the RNA–protein complexation that is important for virus replication and thereby can be considered potential initial candidates for drug discovery (see picture).  |
| Keywords: | biosensors conjugated polyelectrolytes drug screening FRET |