|
|||||
|
|
Accelerated glycosylation under frozen conditions |
|
| Authors: | Maki Takatani Jun Nakano Midori A Arai Hiromichi Ohta |
| Institution: | a RIKEN (The Institute of Physical and Chemical Research), 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan b CREST (JST), Kawaguchi, Saitama 332-0012, Japan c Department of Chemistry, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-0061, Japan |
| Abstract: | O-Glycosylations using thiomethyl glycosides as donors were compared under both frozen and unfrozen conditions. In the presence of MeOTf as a promoter, enormous rate acceleration was observed when the glycosylation was conducted in p-xylene below its freezing point. |
| Keywords: | Glycosylation Frozen Rate acceleration High-mannose type Oligosaccharide |
| 本文献已被 ScienceDirect 等数据库收录！ | |