Sequosempervirin A, a novel spirocyclic compound from Sequoia sempervirens |
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| Authors: | Yu-Mei Zhang Min He Su-Qin Shang |
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| Institution: | a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 650204 Kunming, Yunnan, People's Republic of China
b Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, 100050 Beijing, People's Republic of China |
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| Abstract: | A novel spirocyclic compound (4R)-4-(4-hydroxy-benzyl) spiro 4,5] dec-1-en-8-ol (sequosempervirin A) was isolated from the branches and leaves of Sequoia sempervirens. Its structure and relative stereochemistry were mainly determined by MS, 2D NMR and X-ray means, which is the first naturally occurring norlignan containing one spirocycle with C6 (cyclohexane)-C2-C3-C6 skeleton. |
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| Keywords: | Sequoia sempervirens Taxodiaceae Spirocyclic compound Norlignan Sequosempervirin A |
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