tert‐Butyl (3S,6R,9R)‐(5‐oxo‐3‐{[1(R)‐phenylethyl]carbamoyl}‐1,2,3,5,6,7,8,8a‐octahydroindolizin‐6‐yl)carbamate monohydrate at 95 K |
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Authors: | Raffaella Soave Riccardo Destro |
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Abstract: | The asymmetric unit of the title compound, C22H31N3O4·H2O, incorporates one water molecule, which is hydrogen bonded to the 3‐oxo O atom of the indolizidinone system. The two rings of the peptidomimetic molecule are trans‐fused, with the six‐membered ring having a slightly distorted half‐chair conformation and the five‐membered ring having a perfect envelope conformation. The structure is stabilized by intermolecular O—H?O interactions between the water and adjacent peptide molecules, and by N—H?O interactions between the peptide molecules, which link the molecules into infinite chains. |
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