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O‐Benzyl‐N‐tert‐butoxy­carbonyl‐N‐methyl‐l‐tyrosine
Authors:El bieta Jankowska  Miros&#x;aw Gilski  Mariusz Jasklski  Zbigniew Grzonka  Leszek &#x;ankiewicz
Institution:El?bieta Jankowska,Miros?aw Gilski,Mariusz Jaskólski,Zbigniew Grzonka,Leszek ?ankiewicz
Abstract:The crystal structure of the title compound, alternatively called 3‐4‐(benzyl­oxy)­phenyl]‐2‐(Ntert‐butoxy­car­bonyl‐N‐methyl­amino)­propi­onic acid, C22H27NO5, has been studied in order to ex­amine the role of N‐methyl­ation as a determinant of peptide conformation. The conformation of the tert‐butoxy­carbonyl group is transtrans. The side chain has a folded conformation and the two phenyl rings are effectively perpendicular to one another. The carboxyl­ate hydroxyl group and the urethane carbonyl group form a strong intermolecular O—H?O hydrogen bond.
Keywords:
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