多元协方差分析用于艾滋病疗法的选择

目的:优化HAART药物治疗方案,提高治疗效果,为广大患者和医生选择艾滋病的疗法提供科学的依据.方法:以CD4细胞数的增加值作为体现治疗效果的因变量,治疗时间和初始治疗CD4细胞数为协变量,通过四组疗法分组进行多元协方差分析。结果:患者治疗效果的差异主要是由于治疗方法和治疗时间以及初始治疗cd4值的差异所致;四种疗法的疗效总体上差异显著,满足完备性条件和显著性条件的疗法疗效优劣顺序是:M4>M2≈M3≈M1.结论:多元协方差分析用于艾滋病疗法的选择对实际工作有积极的指导意义.

The Analysis of Multiple Covariance Uses in AIDS Therapy Choice

Objective:Optimizes the HAART medicine plan,enhances the curative effect,provide the science basis for the general patients and doctor to choose the method curing AIDS.Methods Carries on multiple analysis of covariance by the CD4 cell number increase in value as the dependent variable,the treatment time and initial CD4 cell number as covariate variable,therapy as grouping variable.Results: The patient curative effect difference mainly because of the therapy and the treatment time as well as initial CD4 cell number in difference;the four kinds of treatment curative effect difference is notable as a whole.Therapy curative effect quality order is M4(?)M2≈M3≈M1,when satisfies the complete and significance condition.Conclusion:It is both necessary and practical to apply multiple analysis of covariance to AIDS therapy choice.