Chemistry of two-dimensional MXene nanosheets in theranostic nanomedicine |
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| Institution: | 1. SRM Research Institute, SRM Institute of Science and Technology, Kattankulathur 603203, Kanchipuram, India;2. Department of Biomedical Engineering, SRM Institute of Science and Technology, Kattankulathur 603203, Kanchipuram, India;3. Department of Physics and Nanotechnology, SRM Institute of Science and Technology, Kattankulathur 603203, Kanchipuram, India;4. Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603203, Kanchipuram, India;1. Warsaw University of Technology, Faculty of Materials Science and Engineering, 02-507 Warsaw, Wołoska 141, Poland;2. Palacký University, Regional Centre of Advanced Technologies and Materials, 78371 Olomouc, Šlechtitelů 27, Czech Republic;3. Adam Mickiewicz University, NanoBioMedical Centre, 61-614 Poznań, Wszechnicy Piastowskiej 3, Poland;4. Warsaw University of Technology, Faculty of Chemistry, 00-664 Warsaw, Noakowskiego 3, Poland;5. Adam Mickiewicz University, Faculty of Chemistry, 61-614 Poznań, Uniwersytetu Poznańskiego 8, Poland;6. Centre for Advanced Technologies, Adam Mickiewicz University, 61-614 Poznań, Uniwersytetu Poznańskiego 10, Poland;7. Université de Strasbourg, CNRS, ISIS, 67000 Strasbourg, 8 allée Gaspard Monge, France;8. Drexel University, Department of Materials Science and Engineering, Philadelphia, Chestnut Street 3141, PA 19104, USA |
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| Abstract: | Transition metal carbide,carbonitride and nitride MXenes,as the emerging two-dimensional(2D)nanomaterials,have aroused burgeoning research interest in a broad range of applications ranging from energy conversion to biomedicines attributing to their distinctive planar nanostructure,physiochemical properties and biological effects.They are featured with fascinating electronic,optical,magnetic,mechanical and thermal properties,which exert significant roles in biomedical applications of 2D MXenes.In this review,we briefly summarize the recent research progress of 2D MXenes and highlight their intrinsic chemistry in theranostic nanomedicines,focusing on the synthetic chemistry for MXenes construction,surface chemistry for surface engineering,physiochemical property for theranostic application and biological chemistry for biosafety evaluation.Furthermore,based on the current achieve ments on MXenes,their potential research directio n,critical challenges and future development in biomedicine are also discussed.It is highly expected that 2D MXene-based nanosystems would have a broad application prospect in theranostic biomedicine provided the current facing critical issues and challenges are adequately solved. |
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| Keywords: | MXenes Two-dimensional materials Nanomedicine Cancer Theranostic |
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