Abstract: | 2-Amino-5-phenyl-1,3,4-oxadiazole ( 1a ) and 2-amino-1,3,4-thiadiazole ( 1b ) reacted with acrylonitrile to yield β-cyanoethylamino derivatives. On the other hand, 2-amino-4-phenylthiazole ( 2 ) reacted with acrylonitrile under the same experimental conditions to yield a di-β-cyanoethylaminothiazole derivative. 3-Phenyl-Δ2-1,2,4-triazoline-5-thione reacted with acrylonitrile to yield the corresponding adduct. The structure of the adduct was established by its conversion into the acid 13 which could be synthesised via another independent route. |