Cyloadditions of benzopyrones: Rapid access to bicyclic AB-ring analogues of anthracyclines |
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| Authors: | Michael E Jung Richard W Brown Jeffrey A Hagenah Charles E Strouse |
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| Institution: | Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90024 U.S.A. |
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| Abstract: | Cycloaddition of the benzopyrone 10b with 1,1-disubstituted alkenes 12, 14, and 16 produces fair yields of the lactones 13, 15, and 17, AB-ring analogues of the anthracyclines. |
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