Highly efficient and green esterification of carboxylic acids in deep eutectic solvents without any other additives |
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| Authors: | Sumera Yasmin Wen-Bing Sheng Cai-Yun Peng Atta-ur Rahman Duan-Fang Liao |
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| Affiliation: | 1. TCM and Ethnomedicine Innovation &2. Development Laboratory, Sino-Pakistan TCM and Ethnomedicine Research Center, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, P. R. China;3. HEJ, Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan;4. HEJ, Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan |
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| Abstract: | ![]()
A protocol that carboxylic acids esterifies with the quaternary ammonium salt of deep eutectic solvent (DES) is presented, which opens a new access to ester using DES as alkylating agent, solvent, and catalyst. The reaction runs smoothly in DES without any other additives. Substituted cinnamic acids, aromatic acids, and aliphatic acids can be esterified in moderate to good yields. The advantages of this reaction include excellent functional group compatibility and simple reaction procedure. |
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| Keywords: | Carboxylic acids catalyst-free deep eutectic solvent esterification |
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