A novel, one-pot, solvent-, and catalyst-free synthesis of 2-aryl/alkyl-4(3H)-quinazolinones |
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Authors: | Mehdi Adib Samira Ansari Hamid Reza Bijanzadeh |
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Institution: | a School of Chemistry, University College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran b Department of Chemistry, Tarbiat Modarres University, PO Box 14115-175, Tehran, Iran |
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Abstract: | A novel and one-pot synthesis of 2-aryl/alkyl-4(3H)-quinazolinones is described. The in situ prepared amidoximes from the reaction between nitriles and hydroxylamine are condensed with anthranilic acids under solvent- and catalyst-free conditions to produce the title compounds in excellent yields. |
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Keywords: | Anthranilic acids Nitriles Amidoximes 2-Aryl/alkyl-4(3H)-quinazolinones Solvent-free Catalyst-free |
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