Synthesis of oligo-2′-<Emphasis Type="Italic">O</Emphasis>-methylribonucleotides containing α-amino acid residues in 2′-position |
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| Authors: | E V Kazanova E M Zubin V Kachalova D A Stetsenko M J Gait T S Oretskaya |
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| Institution: | (1) Department of Chemistry, M. V. Lomonosov Moscow State University, 1 Leninskie Gory, 119992 Moscow, Russian Federation;(2) Supramolecular and Biomolecular Chemistry Division, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, UK;(3) Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK |
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| Abstract: | Oligo-2′-O-methylribonucleotides containing residues of phenylalanine, histidine, and lysine amides were synthesized with the use of
new phosphoramidites of 2′-aminoacid derivatives of uridine.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 4, pp. 775–783, April, 2007. |
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| Keywords: | nucleosides phosphoramidites oligonucleotides amino acids |
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