| 苯硼酸类糖敏感微凝胶制备及其糖敏感性研究 |
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| 引用本文： | 尹维彬,滕大勇,张新歌,王瑱,李朝兴.苯硼酸类糖敏感微凝胶制备及其糖敏感性研究[J].离子交换与吸附,2008,24(6). |
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| 作者姓名： | 尹维彬 滕大勇 张新歌 王瑱 李朝兴 |
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| 作者单位： | 南开大学高分子化学研究所,功能高分子教育部重点实验室,天津,300071 |
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| 基金项目： | 天津市自然科学基金
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| 摘 要： | 制备了以葡聚糖作为交联剂的氨基苯硼酸类糖敏感微凝胶,用1H-NMR和FT-IR表征了其结构。利用微凝胶的不同条件下的粒径变化,深入研究了该类凝胶对糖浓度的刺激响应行为。结果表明,葡聚糖的引入使微凝胶在生理条件下具有更加优秀的依糖刺激响应行为。
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| 关 键 词： | 糖敏感 微凝胶 苯硼酸 葡聚糖 |
STUDY ON THE SYNTHESIS OF GLUCOSE-SENSITIVE MICROGELS BEARING PHENYLBORATE DERIVATIVES AND THE PROPERTIES OF ITS GLUCOSE RESPONSIVE BEHAVIOR |
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| YIN Weibin,TENG Dayong,ZHANG Xinge,WANG Zhen,LI Chaoxing.STUDY ON THE SYNTHESIS OF GLUCOSE-SENSITIVE MICROGELS BEARING PHENYLBORATE DERIVATIVES AND THE PROPERTIES OF ITS GLUCOSE RESPONSIVE BEHAVIOR[J].Ion Exchange and Adsorption,2008,24(6). |
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| Authors: | YIN Weibin TENG Dayong ZHANG Xinge WANG Zhen LI Chaoxing |
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| Institution: | YIN Weibin TENG Dayong ZHANG Xinge WANG Zhen LI Chaoxing The Key Laboratory of Functional Polymer Materials of Ministry Education,Institute of Polymer Chemistry,Nankai University,Tianjin 300071,China |
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| Abstract: | Glucose-sensitive microgels bearing phenylboronic derivatives were synthesized by using dextran as cross-linker agents and their structures were confirmed by 1H-NMR and FT-IR. Their glucose responsive behavior was studied by monitoring the hydrodynamic diameter (DH) and size distribution of the microgels. The results demonstrated that the novel microgels had more powerful glucose responsive behavior in physiological conditions by the introduction of dextran to them. |
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| Keywords: | Glucose-sensitive Microgels Phenylboronic Dextran |
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